News and resources


Stay up to date on the latest advances with summaries of the key FOP data and other information resources.

Senolytics may have a role to play in FOP treatment

Drugs that selectively induce apoptosis of senescent cells may be effective candidates for the treatment of fibrodysplasia ossificans progressiva (FOP) flare-ups via the inhibition of tissue reprogramming and subsequent prevention of endochondral heterotopic ossification (HO), preclinical study findings indicate.

US FOP prevalence higher than expected

The prevalence of fibrodysplasia ossificans progressiva (FOP) in the US is higher than previously believed, according to research published in the Orphanet Journal of Rare Diseases.

Saracatinib identified as potential FOP treatment

Experimental data suggest that the tyrosine kinase inhibitor saracatinib may be a candidate for the treatment of fibrodysplasia ossificans progressiva (FOP), via its inhibition of activin receptor-like kinase (ALK)2.

FOP great toe shows two developmental phenotypes

A detailed analysis of radiographs from individuals with ACVR1R206H -mutated fibrodysplasia ossificans progressiva (FOP) has found that great toe malformations result from monophalangeal and biphalangeal phenotypes.


Below is a list of additional groups and organizations also aiming to raise awareness and educate on FOP. Please note, being listed here as a resource does not indicate endorsement of our program.

FOP clinical diagnosis quiz image references

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